Research Interests
My major research
interests are the functional organization of the primate visual system
and the neural basis of perception in health and disease. Recently,
I have focused on binocular vision and the neurological characterization
of adults and children with amblyopia (lazy eye).
I approach these topics with studies of normal behavior, the behavioral
effects of focal lesions, and physiological measurement of brain activity.
I currently use functional magnetic resonance imaging (fMRI) techniques
to measure local physiological signals in brain tissue while human subjects
view visual stimuli. I take much of my inspiration from the relatively
well-understood monkey visual system, which is similar to the human
system. Using fMRI and appropriate visual stimulation provides clear,
non-invasive localization of the boundaries of the multiple areas in
human visual cortex, areas known previously only from monkeys. An important
methodological advantage is the use of tools that enable visualization
of brain activation data as a 2-D pattern on the flattened brain, and
facilitate the build-up of increasingly detailed maps of the visual
areas in single subjects.
